Bowenoid papulosis in a patient with AIDS treated with imiquimod: case report.
نویسندگان
چکیده
A 53-year-old male patient with acquired immunodeficiency syndrome (AIDS) was treated with topical immunomodulator imiquimod for bowenoid papular. Clinically the lesions presented as condilomatous and papulous changes with color varying from skin color to grayish. The lesions were located in the glans and in the dorsum of the penis. Clinical diagnosis was confirmed by histopathological examination, and the polymerase chain reaction (PCR) demonstrated the presence of human papilloma virus (HPV) 16. It was decided to apply a topical treatment with imiquimod 5% cream three times a week for 16 weeks. Almost complete regression was obtained; the residual lesions were treated with a combined chemical cauterization by using 50% trichloroacetic acid followed by 25% podophylin. Although it is not a definitive treatment, the use of topical immunomodulator is one more therapeutic option in the selected HPV cases.
منابع مشابه
Successful treatment of bowenoid papulosis in a 9-year-old girl with vertically acquired human immunodeficiency virus.
A 9-year-old black girl with vertically acquired human immunodeficiency virus (HIV) and no history of condyloma acuminata presented with a 4-year history of enlarging and spreading dark brown flat papules in the perineum. Some of the lesions were confluent and extended from the clitoris to the labia majora and posteriorly to the buttocks and perianal region. A biopsy of one of the lesions showe...
متن کاملIsolated extragenital HPV-thirties-group-positive bowenoid papulosis in an AIDS patient.
We report a case of extragenital bowenoid papulosis in a man with AIDS. The lesions occurred on the anterolateral aspects of the neck, and were not associated with clinical genital or periungual involvement. In situ hybridization demonstrated abundant HPV DNA within the thirties group (31/33/35), in the absence of HPV-16 or -18.
متن کاملExtensive bowenoid papulosis of the vulva treated by carbon dioxide laser in a patient with AIDS.
1. Johnson TM, Saluja A, Fader D, Blum D, Cotton J, Wang TS, et al. Isolated extragenital bowenoid papulosis of the neck. J Am Acad Dermatol. 1999;41:867--70. 2. Fader DJ, Stoler MH, Anderson TF. Isolated extragenital HPVthirties-group-positive bowenoid papulosis in an AIDS patient. Br J Dermatol. 1994;131:577--80. 3. Rüdlinger R, Grob R, Yuan XY, Rus WS. Human papillomavirus35-positive bowenoi...
متن کاملExtra-anogenital HPV16-related bowenoid papulosis.
In this report we describe a case of bowenoid papulosis (BP) on the face of a 44 year old Algerian man. To our knowledge this is the first reported case of isolated extragenital BP. The presence of type 16 human papilloma virus was demonstrated by in situ hybridisation. This case underscores that multiple HPV-induced severe intraepithelial neoplasia, the so-called BP, is not restricted to the a...
متن کاملA Case of Isolated Bowenoid Papulosis of the Nipple
Bowenoid papulosis (BP) is a disease that mainly occurs in sexually active young adults. The patients present with multiple pigmented papular lesions with a verrucous surface on the anogenital area. Although extragenital BP is usually associated with concomitant genital involvement, a few cases of isolated extragenital BP have been reported. However, to our knowledge, BP of the nipple has not y...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Acta dermatovenerologica Croatica : ADC
دوره 12 4 شماره
صفحات -
تاریخ انتشار 2004